BDBM50100317 CHEMBL3321822

SMILES NC(=O)c1c(N)n(-c2ccc(NC(=O)Nc3cccc(c3)C(F)(F)F)cc2)c2nc3ccccc3nc12

InChI Key InChIKey=RQXYLZHJULSWPX-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100317   

TargetEphrin type-A receptor 3(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50100317(CHEMBL3321822)
Affinity DataKd:  39.3nMAssay Description:Binding affinity to EphA3 (unknown origin) by surface plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50100317(CHEMBL3321822)
Affinity DataIC50: 89nMAssay Description:Inhibition of phosphorylation of full-length myc-tagged human EphB4 overexpressed in mouse embryonic fibroblasts after 90 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed