BDBM50094702 1H-indole::CHEMBL15844::Indol::Indole, 7::indole

SMILES c1cc2ccccc2[nH]1

InChI Key InChIKey=SIKJAQJRHWYJAI-UHFFFAOYSA-N

Data  5 KI  6 Kd  1 EC50  2 ITC

PDB links: 20 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50094702   

TargetTrp operon repressor(Escherichia coli (strain K12))
University of Chicago

LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKd:  2.51E+4nMAssay Description:Binding assay of L-trptophan and analogues to trp aporepressorMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKd:  3.00E+6nMAssay Description:Inhibition of human adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKd:  3.00E+5nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKd:  3.00E+6nMAssay Description:Dissociation constant against adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKd:  3.00E+5nMAssay Description:Dissociation constant for Leukocyte function associated antigen 1 (LFA-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndolysin [L99A](Enterobacteria phage T4)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKd:  2.90E+5nMAssay Description:Dissociation constant against T4 lysozyme mutant L99AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Kyoto University Shogoin-Kawaharacho

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataEC50:  7.52E+4nMAssay Description:Agonist activity at TRPA1 (unknown origin) by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Human)
Ondokuz Mayis University

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKi:  2.33E+3nMAssay Description:Inhibition of human carbonic anhydrase 4 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ondokuz Mayis University

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKi:  3.63E+3nMAssay Description:Inhibition of human carbonic anhydrase 6 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 3(Bovine)
Ondokuz Mayis University

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKi:  1.76E+4nMAssay Description:Inhibition of bovine carbonic anhydrase 3 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analys...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKi:  2.74E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKi:  3.25E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 50094702   

HostPNGBDBM36284(SAMPL3, H3 | BDBM36303 | Methyl Viologen-Cucurbit[...)
University of Cambridge

GuestPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
ITC DataΔG°: -7.94kcal/mole logk: 6.70E+5
pH: 7.0 T: 25.00°C 
HostPNGBDBM36284(SAMPL3, H3 | BDBM36303 | Methyl Viologen-Cucurbit[...)
University of Cambridge

GuestPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
ITC DataΔG°: -7.19kcal/mole −TΔS°: 2.60kcal/mole ΔH°: -9.79kcal/mole logk: 1.80E+5
pH: 7.0 T: 25.00°C