BDBM50094310 CHEMBL3590112

SMILES CCS(=O)(=O)N1CCc2cnc(NC3CCOCC3)nc2C1

InChI Key InChIKey=IYULUKZVVYXBLY-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094310   

TargetMitogen-activated protein kinase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50094310(CHEMBL3590112)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK2 in human A375 cells harboring B-RAF V600E mutant assessed as decrease in phospho-ERK2 level after 2 hrs by Cellomics ArrayScanTM V...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50094310(CHEMBL3590112)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MEK U911-activated ERK2 (unknown origin) using Erktide as substrate preincubated with enzyme for 20 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50094310(CHEMBL3590112)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of MEK U911-activated ERK2 (unknown origin) using Erktide as substrate preincubated with enzyme for 20 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)