BDBM50092055 (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide::(2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenamide::3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide::4-hydroxyphenyl retinamide::CHEMBL7301::FENRETINIDE::N-(4-HYDROXYPHENYL)ALL-TRANS RETINAMIDE::N-(4-hydroxyphenyl)-retinamide::N-(4-hydroxyphenyl)retinamide::N-(4-hydroxyphenyl)retinamide, 4-HPR

SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)Nc1ccc(O)cc1

InChI Key InChIKey=AKJHMTWEGVYYSE-UHFFFAOYSA-N

Data  5 KI  4 IC50  2 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50092055   

TargetRetinol-binding protein 4(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataEC50:  2.37E+3nMAssay Description:Antagonist activity at His-tagged recombinant human sRBP expressed in Escherichia coli BL21(DE3) assessed as disruption of ROH-sRBP-TTR protein inter...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 2(Mouse)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataIC50: 5.99E+4nMAssay Description:Inhibition of mouse Ido1 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProsaposin(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataKd:  6.90E+3nMAssay Description:Binding affinity to human saposin D (1 to 81 residues) expressed in Escherichia coli at 25 degree C by electronic absorption spectroscopyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProsaposin(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataKd:  6.90E+3nMAssay Description:Binding affinity to human saposin D (1 to 81 residues) expressed in Escherichia coli at 25 degree C by fluorescence quenching spectroscopyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of rat liver microsome DES1 incubated for 20 min in presence of NADH by liquid scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataIC50: 100nMAssay Description:Inhibition of DES1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRetinoic acid receptor gamma(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataKi: >400nMAssay Description:Binding affinity against Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataKi: >2.20E+3nMAssay Description:Binding affinity for retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataKi: >2.80E+3nMAssay Description:Binding affinity for retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataKi: >6.00E+3nMAssay Description:Binding affinity for retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50092055(CHEMBL7301 | N-(4-hydroxyphenyl)-retinamide | 4-hy...)
Affinity DataKi:  8.28E+3nMAssay Description:Inhibition of rat liver microsome DES1 assessed as inhibition constant incubated for 20 mins in presence of NADH by liquid scintillation counter meth...More data for this Ligand-Target Pair
In DepthDetails
PubMed