BDBM50086884 (R)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-9-oxo-1,8-diaza-tricyclo[10.6.1.0*13,18*]nonadeca-12(19),13(18),14,16-tetraen-10-yl)-succinamide::CHEMBL281795::N*4*-Hydroxy-2-isobutyl-N*1*-(9-oxo-1,8-diaza-tricyclo[10.6.1.0*13,18*]nonadeca-12(19),13(18),14,16-tetraen-10-yl)-succinamide::N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YL)-SUCCINAMIDE

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@H]1Cc2cn(CCCCCCNC1=O)c1ccccc21

InChI Key InChIKey=GCBPAPVOMPJQHK-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50086884   

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086884(N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086884(N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human neutrophil gelatinase, matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086884(N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50086884(N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO...)
Affinity DataKi:  1nMAssay Description:binding affinity towards HIV-1 Protease enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086884(N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO...)
Affinity DataKi:  3nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086884(N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO...)
Affinity DataKi:  9nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails Article