BDBM50084216 (R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL151591

SMILES CONC1C[C@@H](N(C1)S(=O)(=O)c1ccc(OC)cc1)C(=O)NO

InChI Key InChIKey=OJLWCTMBGWSVFC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50084216   

Target72 kDa type IV collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084216((R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against gelatinase-A (matrix metalloprotease-2).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084216((R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50: 3.39E+3nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloprotease-7, MMP-7)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084216((R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50: 212nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloprotease-1, MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084216((R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084216((R)-4-Methoxyamino-1-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of human recombinant collagenase-3 (Matrix metalloprotease-13)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed