BDBM50084149 CHEMBL3425952

SMILES COCCCNC(=O)c1nc(no1)-c1cccc2[nH]ccc12

InChI Key InChIKey=BPSPJIVDNLKGAJ-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084149   

TargetHematopoietic prostaglandin D synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084149(CHEMBL3425952)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition fluorescein-conjugated ligand binding to human HPGDS expressed in Escherichia coli by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084149(CHEMBL3425952)
Affinity DataIC50: 170nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084149(CHEMBL3425952)
Affinity DataKd:  650nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed