BDBM50079356 CHEMBL511201

SMILES c1cc(c(c(c1OCc2nc3cc(cnc3s2)Cl)F)C(=O)N)F

InChI Key InChIKey=INYJNSBDHOVLAH-UHFFFAOYSA-N

Data  4 IC50  1 Kd  1 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50079356   

TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataKd: <100nMAssay Description:Displacement of free fluorescent probe from inter domain cleft of stabilized Bacillus subtilis FtsZ assessed as dissociation constant in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 150nMAssay Description:Inhibition of Staphylococcus aureus FTsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataEC50:  4.00E+3nMAssay Description:Activation of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)