BDBM50078117 (1R,2R,3R,4S,5R)-4-AMINO-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOL::(1R,2R,3R,4S,5R)-4-Amino-5-methylsulfanyl-cyclopentane-1,2,3-triol::CHEMBL9623::Mannostatin A, 1::Mannostatin A, 1a

SMILES CS[C@@H]1[C@@H](N)[C@@H](O)[C@@H](O)[C@H]1O

InChI Key InChIKey=BLOFGONIVNXZME-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50078117   

TargetMannosyl-oligosaccharide alpha-1,2-mannosidase IA(Fruit fly)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50078117(Mannostatin A, 1 | (1R,2R,3R,4S,5R)-4-Amino-5-meth...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Drosophila melanogaster GM2b by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM50078117(Mannostatin A, 1 | (1R,2R,3R,4S,5R)-4-Amino-5-meth...)
Affinity DataKi:  36nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-mannosidase 2(Human)
University of Georgia

LigandPNGBDBM50078117(Mannostatin A, 1 | (1R,2R,3R,4S,5R)-4-Amino-5-meth...)
Affinity DataKi:  90nM ΔG°:  -9.99kcal/molepH: 5.6 T: 2°CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-mannosidase 2(Human)
University of Georgia

LigandPNGBDBM50078117(Mannostatin A, 1 | (1R,2R,3R,4S,5R)-4-Amino-5-meth...)
Affinity DataKi:  210nM ΔG°:  -9.47kcal/molepH: 5.6 T: 2°CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed