BDBM50076341 (S)-N-Methyl-3-pentafluorophenyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide::2-[3-(5-MERCAPTO-[1,3,4]THIADIAZOL-2YL)-UREIDO]-N-METHYL-3-PENTAFLUOROPHENYL-PROPIONAMIDE::CHEMBL290140::PNU-142372

SMILES CNC(=O)[C@H](Cc1c(F)c(F)c(F)c(F)c1F)NC(=O)Nc1nnc(S)s1

InChI Key InChIKey=HZAXNPDJVFUGDS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50076341   

TargetStromelysin-1(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50076341(PNU-142372 | (S)-N-Methyl-3-pentafluorophenyl-2-[3...)
Affinity DataKi:  18nMAssay Description:Binding affinity for matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50076341(PNU-142372 | (S)-N-Methyl-3-pentafluorophenyl-2-[3...)
Affinity DataKi:  18nMAssay Description:Inhibition of human stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50076341(PNU-142372 | (S)-N-Methyl-3-pentafluorophenyl-2-[3...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity for matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50076341(PNU-142372 | (S)-N-Methyl-3-pentafluorophenyl-2-[3...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human Matrix metalloprotease-2 (gelatinase-A)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed