BDBM50075101 CHEMBL3414624

SMILES CCCN[C@@H](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=ZDIZXAAADLAUDS-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50075101   

TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50075101(CHEMBL3414624)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human PRMT1 (10 to 352) using RGG peptide as substrate assessed as transfer of [3H]-Me of [3H-Me]-SAM to peptide substrate after 1.5 hr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50075101(CHEMBL3414624)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CARM1 (19 to 608) using histamine H3 (1 to 40) as substrate assessed as transfer of [3H]-Me of [3H-Me]-SAM to peptide substrate a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50075101(CHEMBL3414624)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of full-length human SETD7 using histamine H3 (1 to 21) as substrate assessed as transfer of [3H]-Me of [3H-Me]-SAM to peptide substrate a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone-lysine N-methyltransferase SETD2(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50075101(CHEMBL3414624)
Affinity DataIC50: 800nMAssay Description:Inhibition of human SETD2 (1347 to 1711) using histamine H3 (20 to 50) as substrate assessed as transfer of [3H]-Me of [3H-Me]-SAM to peptide substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase NSD2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50075101(CHEMBL3414624)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human MMSET (973 to 1203 residues) expressed in Escherichia coli BL21 (DE3) using S-adenosyl-methionine as substrate incubated for 60 m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50075101(CHEMBL3414624)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of 15N-labeled NSD2 (953 to 1240 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 using H3K36 as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed