BDBM50061168 CHEMBL3393706

SMILES Fc1cccc(F)c1-c1ccc2[nH]nc(-c3cncc(O[C@H]4CNCCC44CC4)n3)c2c1

InChI Key InChIKey=FCGLYPSBPNFQRF-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50061168   

LigandPNGBDBM50061168(CHEMBL3393706)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061168(CHEMBL3393706)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length recombinant Pim-2 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061168(CHEMBL3393706)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of full length recombinant Pim-1 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061168(CHEMBL3393706)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of full length recombinant Pim-3 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed