BDBM50054825 CHEMBL356301::[(S)-7-([4,4']Bipiperidinyl-1-carbonyl)-4-methyl-3-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-2-yl]-acetic acid

SMILES CN1Cc2cc(ccc2N[C@@H](CC(O)=O)C1=O)C(=O)N1CCC(CC1)C1CCNCC1

InChI Key InChIKey=PYZOVVQJTLOHDG-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054825   

TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50054825([(S)-7-([4,4']Bipiperidinyl-1-carbonyl)-4-methyl-3...)
Affinity DataKd:  1.90nMAssay Description:Inhibition of alpha IIb beta III mediated platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50054825([(S)-7-([4,4']Bipiperidinyl-1-carbonyl)-4-methyl-3...)
Affinity DataIC50: 28nMAssay Description:inhibition of ADP-induced platelet aggregation in human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50054825([(S)-7-([4,4']Bipiperidinyl-1-carbonyl)-4-methyl-3...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)