BDBM50054272 CHEMBL3319391::US9522881, 11c-9 (L88N79)

SMILES Cn1c(c(I)c2cc(C(O)=O)c(O)cc12)-c1cccc(NC(=O)CCC(=O)NCc2ccc3OCOc3c2)c1

InChI Key InChIKey=RYALHYUYZACQOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054272   

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM50054272(US9522881, 11c-9 (L88N79) | CHEMBL3319391)
Affinity DataIC50: 1.40E+4nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50054272(US9522881, 11c-9 (L88N79) | CHEMBL3319391)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using p-nitrophenyl phosphate substrate by microplate spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed