BDBM50052553 (2S)-2-aminohexanedioic acid::(S)-2-aminohexanedioic acid::CHEMBL88804::L-2-aminoadipic acid

SMILES N[C@@H](CCCC(O)=O)C(O)=O

InChI Key InChIKey=OYIFNHCXNCRBQI-UHFFFAOYSA-N

Data  5 KI  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50052553   

TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50:  3.50E+4nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >3.00E+6nMAssay Description:Effect on Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50:  3.50E+4nMAssay Description:Effect on Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >1.00E+6nMAssay Description:Effect on Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 6(Rat)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50:  1.40E+5nMAssay Description:Effect on Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50:  1.40E+5nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50:  3.50E+4nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >3.00E+6nMAssay Description:Agonistic activity at mGlu4a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >3.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataKi:  3.50E+4nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataKi: >1.00E+6nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataKi:  1.40E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataKi: >1.00E+6nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataKi: >3.00E+6nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed