BDBM50050521 (2-Dihydroxyborane-pyrrolidin-1-yl)-pyrrolidin-2-yl-methanone(PBP)::(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE::Boronic acid derivative::CHEMBL63895::US11096924, DASH-inhibitors 1181::US11559537, Compound 1181
SMILES OB(O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1
InChI Key InChIKey=XSBZZZGVAIXJLD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50050521
Affinity DataIC50: 5.40E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+7nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+5nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMpH: 2.0Assay Description:The inhibitor solution is prepared by dissolving 3-5 mg of inhibitor in pH 2 solution (0.01 N HCl), such that the concentration of the solution is eq...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Affinity DataIC50: 4.71E+5nMAssay Description:Inhibitory activity against aminopeptidase N assayed by the L-Ala-MCA method.More data for this Ligand-Target Pair
Affinity DataIC50: 8.48E+4nMAssay Description:Inhibitory activity against dipeptidyl peptidase IV (DPP- IV)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro for inhibition of Dipeptidylpeptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Compound was tested in vitro for inhibition of Dipeptidylpeptidase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+4nMpH: 8.0Assay Description:The inhibitor solution is prepared by dissolving 3-5 mg of inhibitor in pH 2 solution (0.01 N HCl), such that the concentration of the solution is eq...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:In vitro test for inhibitory activity against human dipeptidyl peptidase IV.More data for this Ligand-Target Pair