BDBM50049435 CHEMBL1968515

SMILES O=C1CN2C(COc3ccccc23)=NN1

InChI Key InChIKey=PNPBXXNNLJGHBP-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50049435   

TargetProtein kinase C theta type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049435(CHEMBL1968515)
Affinity DataIC50: 4.53E+5nMAssay Description:Inhibition of human recombinant PKCtheta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFocal adhesion kinase 1(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049435(CHEMBL1968515)
Affinity DataIC50: 1.56E+5nMAssay Description:Inhibition of FAK (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProtein kinase C alpha type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049435(CHEMBL1968515)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant PKCalpha expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049435(CHEMBL1968515)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant PKCtheta by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed