BDBM50039974 CHEMBL3358341

SMILES CN1CCN(CC1)c1ccc(Nc2cc(cn(C)c2=O)-c2cccc(N3CCc4cc(cc(F)c4C3=O)C(C)(C)C#N)c2CO)nc1

InChI Key InChIKey=AGMLIXLHTZGRPZ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50039974   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50039974(CHEMBL3358341)
Affinity DataIC50: 50nMAssay Description:Inhibition of BTK in human whole blood assessed as decrease in CD69 positive cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)