BDBM50038419 CHEMBL50112::N-(1-Benzyl-piperidin-4-yl)-4-iodo-benzamide

SMILES Ic1ccc(cc1)C(=O)NC1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=HELCSESNNDZLFM-UHFFFAOYSA-N

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50038419   

TargetSigma non-opioid intracellular receptor 1(Human)
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50038419(N-(1-Benzyl-piperidin-4-yl)-4-iodo-benzamide | CHE...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity against sigma-1 receptor in guinea pig brain using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50038419(N-(1-Benzyl-piperidin-4-yl)-4-iodo-benzamide | CHE...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Human)
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50038419(N-(1-Benzyl-piperidin-4-yl)-4-iodo-benzamide | CHE...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human sigma 1 receptorMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50038419(N-(1-Benzyl-piperidin-4-yl)-4-iodo-benzamide | CHE...)
Affinity DataKi:  25nMAssay Description:Binding affinity to human sigma 2 receptorMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetD(2) dopamine receptor(Rat)
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50038419(N-(1-Benzyl-piperidin-4-yl)-4-iodo-benzamide | CHE...)
Affinity DataKi:  382nMAssay Description:Binding affinity against D-2 dopamine receptor in rat brain membranes using [3H](-)-sulpiride as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed