BDBM50031337 CHEMBL3358097

SMILES COc1ccc(cc1OCCNS(C)(=O)=O)-c1nc([C@@H](C)Sc2nc(N)cc(N)n2)c(C)s1

InChI Key InChIKey=MBPWFMBRNJJXFY-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031337   

TargetDeoxycytidine kinase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50031337(CHEMBL3358097)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxycytidine kinase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50031337(CHEMBL3358097)
Affinity DataIC50: 28nMAssay Description:Apparent inhibition of human dCK assessed as phosphorylation activity by spectroscopic NADH-dependent enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxycytidine kinase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50031337(CHEMBL3358097)
Affinity DataKi:  9.20nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed