BDBM50029196 (E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid ethyl ester::(E)-ethyl 3-(3,4-dihydroxyphenyl)acrylate::3-(3,4-Dihydroxy-phenyl)-acrylic acid ethyl ester::CHEMBL17347::Ethyl 1-(3',4'-dihydroxyphenyl)propenate::Ethyl caffeate::ethyl 3-(3,4-dihydroxyphenyl)acrylate

SMILES CCOC(=O)\C=C\c1ccc(O)c(O)c1

InChI Key InChIKey=WDKYDMULARNCIS-UHFFFAOYSA-N

Data  4 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029196   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50029196(ethyl 3-(3,4-dihydroxyphenyl)acrylate | (E)-3-(3,4...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against HIV-1 integrase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50029196(ethyl 3-(3,4-dihydroxyphenyl)acrylate | (E)-3-(3,4...)
Affinity DataEC50:  2.30E+4nMAssay Description:Inhibition of TTR V30M mutant (unknown origin) expressed in Escherichia coli assessed as inhibition of amyloid fibril formation by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50029196(ethyl 3-(3,4-dihydroxyphenyl)acrylate | (E)-3-(3,4...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of 5-lipoxygenase of rat basophilic leukemia (RBL) cell cytosolic enzymesMore data for this Ligand-Target Pair
In DepthDetails Article

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50029196(ethyl 3-(3,4-dihydroxyphenyl)acrylate | (E)-3-(3,4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against HIV-1 Integrase (HIV-1-IN)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50029196(ethyl 3-(3,4-dihydroxyphenyl)acrylate | (E)-3-(3,4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 integrase by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed