BDBM50020035 CHEMBL3287849

SMILES O=c1cc(o[nH]1)[C@H]1CCN[C@@H](Cc2ccccc2)C1

InChI Key InChIKey=LNFPEBXLWIXQLF-UHFFFAOYSA-N

Data  9 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50020035   

TargetPlasminogen(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50020035(CHEMBL3287849)
Affinity DataIC50: 950nMAssay Description:Binding affinity to human full length Glu-plasminogen in buffer assessed as inhibition of interaction with fibrin preincubated for 15 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50020035(CHEMBL3287849)
Affinity DataIC50: 2.00E+7nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50020035(CHEMBL3287849)
Affinity DataIC50: 2.00E+7nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50020035(CHEMBL3287849)
Affinity DataIC50: 2.00E+7nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50020035(CHEMBL3287849)
Affinity DataIC50: 2.00E+7nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50020035(CHEMBL3287849)
Affinity DataIC50: 2.00E+7nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50020035(CHEMBL3287849)
Affinity DataIC50: 2.00E+7nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50020035(CHEMBL3287849)
Affinity DataIC50: 280nMAssay Description:Binding affinity to full length Glu-plasminogen in human plasma assessed as inhibition of interaction with fibrin in presence of tPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50020035(CHEMBL3287849)
Affinity DataIC50: 1.00E+9nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed