BDBM50017233 CHEMBL592::LEVO-DROMORAN::LEVORPHANOL
SMILES CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc31
InChI Key InChIKey=JAQUASYNZVUNQP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 42 hits for monomerid = 50017233
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory potency against Opioid receptor mu 1 in the guinea pig ileum assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against opioid receptor mu of guinea pig brain using [3H]DAGO radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibitory activity against Opioid receptor delta 1 of guinea pig was determined by using [3H]DADLE radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro binding affinity against cloned human Opioid receptor kappa 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as reduction in ASP+ substrate uptake by microplate reader based analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Mouse)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:In vitro binding affinity against cloned human Opioid receptor delta 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 278nMAssay Description:Inhibitory potency against Opioid receptor mu 1 in mouse vas deferens assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.00400nMAssay Description:50% Inhibition of stereospecific [3H]-naltrexone (10e-9 M) binding towards opiate receptor in rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptors expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibitory activity against Opioid receptor mu 1 in chinese Hamster Ovary (CHO) cells membranes was determined using [3H]-DAMGO radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Binding affinity towards Opioid receptor mu 1 in guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Binding affinity to MOR (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Binding affinity against opioid receptor mu 1 using [3H]DAMGO as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity for mouse opioid receptor muMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity for mouse sigma opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity towards Opioid receptor kappa 1 in guinea pig brain membranes using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]U-69593 from human kappa opioid receptors expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibitory activity against Opioid receptor kappa 1 in chinese Hamster Ovary (CHO) cell membranes was determined using [3H]U-69593 radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Agonistic activity against kappa opioid receptor in Chinese hamster ovary membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity to KOR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]-U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Binding affinity to human DOR assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Binding affinity towards Opioid receptor delta 1 in guinea pig brain membranes using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]-naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptors expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition of [3H]naltrindole binding to opioid receptor delta 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]Naltindole from human delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Binding affinity against opioid receptor delta 1 using [3H]naltrindole as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibitory activity against Opioid receptor delta 1 in chinese Hamster Ovary (CHO) cell membranes was determined using [3H]naltrindole radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity for mouse opioid receptor kappaMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electric eel)
University of Innsbruck and Center For Molecular Biosciences Innsbruck-Cmbi
Curated by ChEMBL
University of Innsbruck and Center For Molecular Biosciences Innsbruck-Cmbi
Curated by ChEMBL
Affinity DataKi: 2.50E+4nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair