BDBM50016706 CHEMBL63139::Octahydro-indolizine-1,2,8-triol::Swainsonine::Tridolgosir::US20240190866, Compound Swainsonine

SMILES [H][C@@]12[C@H](O)[C@H](O)CN1CCC[C@H]2O

InChI Key InChIKey=FXUAIOOAOAVCGD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016706   

TargetAlpha-mannosidase 2C1(Rat)
Csiro Division of Chemicals and Polymers

Curated by ChEMBL
LigandPNGBDBM50016706(CHEMBL63139 | Octahydro-indolizine-1,2,8-triol | S...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysosomal alpha-mannosidase(Human)
Academia Sinica

US Patent
LigandPNGBDBM50016706(CHEMBL63139 | Octahydro-indolizine-1,2,8-triol | S...)
Affinity DataIC50: 80nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAlpha-mannosidase 2(Human)
Academia Sinica

US Patent
LigandPNGBDBM50016706(CHEMBL63139 | Octahydro-indolizine-1,2,8-triol | S...)
Affinity DataIC50: 40nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
In DepthDetails
US Patent