BDBM50009126 5-Fluoro-1H-indole-2-carboxylic acid::5-fluoroindole-2-carboxylic acid::CHEMBL23507::cid_1820

SMILES OC(=O)c1cc2cc(F)ccc2[nH]1

InChI Key InChIKey=WTXBRZCVLDTWLP-UHFFFAOYSA-N

Data  2 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50009126   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50009126(CHEMBL23507 | cid_1820 | 5-Fluoro-1H-indole-2-carb...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50009126(CHEMBL23507 | cid_1820 | 5-Fluoro-1H-indole-2-carb...)
Affinity DataKd:  2.90E+3nMAssay Description:Dissociation constant for HCV NS3 protease substrate binding siteMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50009126(CHEMBL23507 | cid_1820 | 5-Fluoro-1H-indole-2-carb...)
Affinity DataIC50: 2.97E+5nMAssay Description:Competitive inhibition of PDK1 using [gamma-33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM50009126(CHEMBL23507 | cid_1820 | 5-Fluoro-1H-indole-2-carb...)
Affinity DataIC50: 2.90E+6nMAssay Description:Inhibition of HIV-1 reverse transcriptase RT52A mutant using ABTS as substrate preincubated with compound for 1 hr followed by template-primer additi...More data for this Ligand-Target Pair
In DepthDetails
PubMed