BDBM50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide
SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC
InChI Key InChIKey=AADCDMQTJNYOSS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 56 hits for monomerid = 50007518
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at DRD2 (unknown origin) expressed in HEK293T cells transfected with Galphai1-RLuc8 and gamma2-GFP10 assessed as inhibition of qu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:Tested in vitro for inhibition of [3H]spiperone binding to dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKd: 0.170nMAssay Description:Affinity constant of compound was evaluated in rat striatum tissue preparation.More data for this Ligand-Target Pair
Affinity DataKd: 0.170nMAssay Description:Evaluated in vivo for the affinity towards Dopamine receptor D2 of rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal dopamine receptor D2 was determined in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 0.0860nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Compound was evaluated for the inhibition constant against dopamine receptor D2 in ratMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 0.107nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by MicroBeta scintillation cou...More data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]N-methylspiperone from human D3R expressed in HEK293 cell membranes incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.117nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by MicroBeta scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 0.134nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Compound was measured for its ability to compete with [125I]NCQ298 binding to the human Dopamine receptor D3 transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]N-methylspiperone from human D2R expressed in HEK293 cell membranes incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.990nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]N-methylspiperone from human D4R expressed in HEK293 cell membranes incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair