BDBM50007406 1-(3-(trifluoromethyl)phenyl)piperazine::1-(3-Trifluoromethyl-phenyl)-piperazine::1-(3-Trifluoromethyl-phenyl)-piperazine(TFMPP)::CHEMBL274866::TFMPP
SMILES FC(F)(F)c1cccc(c1)N1CCNCC1
InChI Key InChIKey=KKIMDKMETPPURN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 76 hits for monomerid = 50007406
Affinity DataIC50: 51nMAssay Description:Concentration necessary to achieve half maximal inhibition of [125I]- Iodocyanopindolol binding to 5-hydroxytryptamine 1B receptor at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 2 receptor of rat anterior cortex using [3H]ketanserin as the radiolig...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Displacement of [3H]8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]5-HT as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]mesulergine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Binding affinity (Ki) to rat cortical membranes at 5-HT1B binding site by using [125 I] ICYP as a radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Binding affinity in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 81nMAssay Description:Binding affinity in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 116nMAssay Description:Intrinsic affinity towards serotonin receptor from rat frontal cortex by displacement of [3H]5-HTMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Binding affinity to 5-hydroxytryptamine 2 receptor in rat frontal cortical membranes by [3H]- KET displacement.More data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor of rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
Affinity DataKi: 175nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 175nMAssay Description:Evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat brainMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database