BDBM492902 US10981899, Example RU-0204277-LRE1

SMILES Nc1nc(Cl)cc(n1)N(Cc1cccs1)C1CC1

InChI Key InChIKey=PDWZXKSZLRVSEH-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 492902   

TargetAdenylate cyclase type 10(Human)
Cornell University

US Patent
LigandPNGBDBM492902(US10981899, Example RU-0204277-LRE1)
Affinity DataIC50: 3.30E+3nMAssay Description:The RapidFire 365 High-throughput MS System (Agilent Technologies; RF-MSS) can process samples every 15 seconds allowing analysis of a 384 well plate...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetAdenylate cyclase type 10(Human)
Cornell University

US Patent
LigandPNGBDBM492902(US10981899, Example RU-0204277-LRE1)
Affinity DataIC50: 6.30E+3nMAssay Description:INS-1E insulinoma cells were incubated in 2.5 mM glucose Krebs-Ringer buffer (pH 7.5) supplemented with 2 mM sodium bicarbonate, 10 mM HEPES, and 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetAdenylate cyclase type 10(Human)
Cornell University

US Patent
LigandPNGBDBM492902(US10981899, Example RU-0204277-LRE1)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)