BDBM491353 US10975056, Example 318

SMILES CCc1c(C#N)c(SC(C(N)=O)c2ccccc2)nc(N2CCCN(CCO)CC2)c1C#N

InChI Key InChIKey=IHXXDZHXEBKTKE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491353   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM491353(US10975056, Example 318)
Affinity DataIC50: 320nMAssay Description:Biochemical activity of DNMT1 analyzed using SPA technology. Plates (Griener 784075) were pre-stamped with 100 nL/well of compound (11-point, 3-fold ...More data for this Ligand-Target Pair
In DepthDetails
US Patent