BDBM491136 2-Amino-N-(4-(((3,5-dicyano-4-ethyl-6-(4-methyl-1,4-diazepan-1-yl)pyridin-2-yl)thio)methyl)benzyl)acetamide::US10975056, Example 80

SMILES CCc1c(C#N)c(SCc2ccc(CNC(=O)CN)cc2)nc(N2CCCN(C)CC2)c1C#N

InChI Key InChIKey=QPLFMVVUDGWTPG-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491136   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM491136(US10975056, Example 80 | 2-Amino-N-(4-(((3,5-dicya...)
Affinity DataIC50: 320nMAssay Description:Biochemical activity of DNMT1 analyzed using SPA technology. Plates (Griener 784075) were pre-stamped with 100 nL/well of compound (11-point, 3-fold ...More data for this Ligand-Target Pair
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US Patent
PDB3D3D Structure (crystal)