BDBM468872 US10807959, Example B5

SMILES CC(NC(=O)c1cccc(CNC2=NCCN2)c1)c1cccc(Cl)c1

InChI Key InChIKey=ZHGJIKXLESXIHK-UHFFFAOYSA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 468872   

TargetWD repeat-containing protein 5(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM468872(US10807959, Example B5)
Affinity DataKd:  22nMAssay Description:Inhibition of human WDR5 WIN site expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetWD repeat-containing protein 5(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM468872(US10807959, Example B5)
Affinity DataKi:  30.8nMAssay Description:FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...More data for this Ligand-Target Pair
In DepthDetails
US Patent