BDBM438155 US10618897, Example 23

SMILES FC(F)(F)CNC(=O)CN1C(=O)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3n2)c2c1cccc2Br

InChI Key InChIKey=UXEXYURPAPXPSR-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 438155   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438155(US10618897, Example 23)
Affinity DataIC50: 25.6nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438155(US10618897, Example 23)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant GST-tagged human DDR1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDiscoidin domain-containing receptor 2(Human)
Daegu-Gyeongbuk Medical Innovation Foundation (Dgmif)

Curated by ChEMBL
LigandPNGBDBM438155(US10618897, Example 23)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant GST-tagged human DDR2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Daegu-Gyeongbuk Medical Innovation Foundation (Dgmif)

Curated by ChEMBL
LigandPNGBDBM438155(US10618897, Example 23)
Affinity DataIC50: 29nMAssay Description:Inhibition of DDR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed