BDBM434254 US10562891, Example 176::US11008308, Example 176

SMILES Fc1cc(NC2CCCC2)cc2nc(CSC3CCNCC3)[nH]c(=O)c12

InChI Key InChIKey=YZDTVOCBHYWUNM-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 434254   

TargetProtein mono-ADP-ribosyltransferase PARP14 [1611-1801](Human)
Ribon Therapeutics

US Patent

LigandBDBM434254(US10562891, Example 176 | US11008308, Example 176)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In DepthDetails
Copy BDB DOIUS Patent
PDB3D Structure (crystal)
Copy reaction URL

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Ribon Therapeutics

US Patent

LigandBDBM434254(US10562891, Example 176 | US11008308, Example 176)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In DepthDetails
Copy BDB DOIUS Patent
PDB3D Structure (crystal)
Copy reaction URL

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Ribon Therapeutics

US Patent

LigandBDBM434254(US10562891, Example 176 | US11008308, Example 176)Copy SMILESCopy InChI

Affinity DataIC50: 19nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In DepthDetails
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL