BDBM416580 3-(7-ethoxynaphthalen-2-yl)-1-isobutyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine::US10307425, Example 47::US10632122, Example 47

SMILES CCOc1ccc2ccc(cc2c1)-c1nn(CC(C)C)c2ncnc(N)c12

InChI Key InChIKey=AEVLTZJWDLNUCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 416580   

TargetCAM kinase, CDPK family TgCDPK1(Toxoplasma gondii (strain ATCC 50861 / VEG))
University of Washington

US Patent
LigandPNGBDBM416580(US10307425, Example 47 | 3-(7-ethoxynaphthalen-2-y...)
Affinity DataIC50: 10.8nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

US Patent
LigandPNGBDBM416580(US10307425, Example 47 | 3-(7-ethoxynaphthalen-2-y...)
Affinity DataIC50: 10.8nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
In DepthDetails
US Patent