BDBM36403 (3R)-3-(1,2,3,4-Tetrahydroisoquinolin-7-yloxymethyl)-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine, 16::CID24894155

SMILES NC1=N[C@H](COc2ccc3CCNCc3c2)COc2ccsc12

InChI Key InChIKey=UDFXWCLBONUMNA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36403   

TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM36403(CID24894155 | (3R)-3-(1,2,3,4-Tetrahydroisoquinoli...)
Affinity DataIC50: 400nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM36403(CID24894155 | (3R)-3-(1,2,3,4-Tetrahydroisoquinoli...)
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36403(CID24894155 | (3R)-3-(1,2,3,4-Tetrahydroisoquinoli...)
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed