BDBM34064 2-arylbenzimidazole::CHEMBL179583

SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2ccc(Cl)cc2)cc1

InChI Key InChIKey=UXGJAOIJSROTTN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 34064   

LigandPNGBDBM34064(CHEMBL179583 | 2-arylbenzimidazole)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:NSC 109555 was diluted in water. All other drugs were dissolved in DMSO, in which case the final DMSO concentration in reactions was 10%, and the con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM34064(CHEMBL179583 | 2-arylbenzimidazole)
Affinity DataIC50: 15nMAssay Description:Inhibition of Chk2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM34064(CHEMBL179583 | 2-arylbenzimidazole)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM34064(CHEMBL179583 | 2-arylbenzimidazole)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM34064(CHEMBL179583 | 2-arylbenzimidazole)
Affinity DataIC50: 16nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM34064(CHEMBL179583 | 2-arylbenzimidazole)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM34064(CHEMBL179583 | 2-arylbenzimidazole)
Affinity DataIC50: 15nMAssay Description:Inhibition of Chk2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed