BDBM33284 BMC164883 Compound 53::phenylpropanoic acid derivative, 10

SMILES Cc1oc(nc1CCCc1ccc(C[C@@H](C(O)=O)n2cccc2)cc1)-c1ccccc1

InChI Key InChIKey=QPJVYLQOALFBLJ-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 33284   

LigandPNGBDBM33284(BMC164883 Compound 53 | phenylpropanoic acid deriv...)
Affinity DataIC50: 185nM EC50:  140nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR gamma ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysin...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM33284(BMC164883 Compound 53 | phenylpropanoic acid deriv...)
Affinity DataIC50: 912nM EC50:  623nMT: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM33284(BMC164883 Compound 53 | phenylpropanoic acid deriv...)
Affinity DataIC50: 912nM EC50:  623nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM33284(BMC164883 Compound 53 | phenylpropanoic acid deriv...)
Affinity DataIC50: 185nM EC50:  140nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed