BDBM33224 pyrimidin-2-amine, 12

SMILES Nc1ncc(\N=N\c2ccccc2)c(n1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=UNJMNJFPEVJCQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 33224   

TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM33224(pyrimidin-2-amine, 12)
Affinity DataIC50: 1.56E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed