BDBM31883 9-cis-retinoic acid (9cRA)::ALL-TRANS-RETINOIC ACID::AT-RA::Atralin::CHEMBL38::MLS000028588::SMR000058245::TRETINOIN::Vitamin A acid::[3H]RA::[3H]Retinoic acid::[3H]Vitamin A acid::[3H]tretinoin::all-trans retinoic acid::cid_444795
SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
InChI Key InChIKey=SHGAZHPCJJPHSC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 258 hits for monomerid = 31883
Affinity DataKd: 0.200nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
Affinity DataKd: 0.400nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
Affinity DataKd: 0.400nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh
Curated by PubChem BioAssay
University of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 2.71E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
Affinity DataKd: 13nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: 3.41E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh
Curated by PubChem BioAssay
University of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 4.86E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: >9.51E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh
Curated by PubChem BioAssay
University of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 4.86E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh
Curated by PubChem BioAssay
University of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 4.29E+4nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
Affinity DataKd: 40nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
Affinity DataKd: 30nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: 2.54E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 6(Rat)
University of Pittsburgh
Curated by PubChem BioAssay
University of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 6(Rat)
University of Pittsburgh
Curated by PubChem BioAssay
University of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 6(Rat)
University of Pittsburgh
Curated by PubChem BioAssay
University of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...More data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Binding affinity for Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Transactivation potency for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity for Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Transactivation potency for Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+3nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor gamma using transactivation a...More data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoic acid receptor gamma using transactivatio...More data for this Ligand-Target Pair
Affinity DataEC50: 900nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor alpha using transactivation a...More data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Effective concentration for retinoic acid receptor RAR alpha transcriptional activationMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity for retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Ability to inhibit TTNPB-induced transactivation at retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Agonistic activity against Retinoic acid receptor RAR beta in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.21E+3nMAssay Description:Transcriptional activation in CV-1 cells expressing mouse Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.02E+3nMAssay Description:Transcriptional activation in CV-1 cells expressing human Retinoid X receptor RXR-alphaMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding constant for baculovirus-expressed Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding constant for baculovirus-expressed Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 9nMAssay Description:Relative activity against Retinoid X receptor RXR-alpha compared to 9-cis-RAMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 87nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of [3H]ATRA binding to baculovirus expressed Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 530nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 105nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 563nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.08E+3nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Binding affinity against retinoic Acid gamma receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Binding affinity against retinoic Acid alpha receptors co-transfected into CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against retinoic Acid X beta receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Binding affinity against retinoic Acid X gamma receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair