BDBM30185 CHEMBL226403::Pyrrolopyridine, 16

SMILES O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1cnc2ccccc2c1

InChI Key InChIKey=OWFLADWRSCINST-UHFFFAOYSA-N

Data  9 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 30185   

LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50: 8.5nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
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LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50: 3.44E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50: 5.70E+3nMAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50: 2.00E+5nMAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50: 2.00E+5nMAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant MK2 expressed in Escherichia coli BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataEC50:  49nMAssay Description:Inhibition of MK2 pretreated for 30 mins before substrate addition measured after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50: 100nMAssay Description:Inhibition of MAPKAPK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed