BDBM294478 1-(2-(2-(5,8-dimethyl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)ethyl)-1-methyl-1H-imidazol-4-yl)pyrrolidin-2-one::US9586970, 1

SMILES Cc1cnc(C)n2nc(CCc3nc(cn3C)N3CCCC3=O)nc12

InChI Key InChIKey=GIKLNBNHTSSEKI-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294478   

LigandPNGBDBM294478(US9586970, 1 | 1-(2-(2-(5,8-dimethyl-[1,2,4]triazo...)
Affinity DataIC50: 39nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent
PDB3D3D Structure (crystal)