BDBM29320 BMS-665139::oxazolidin-2-imine, 6c

SMILES Cc1c(Cl)c(ccc1\N=C1/O[C@H]([C@@H]2[C@@H](O)CCN12)C(F)(F)F)C#N

InChI Key InChIKey=KALFKWQLCWAXJO-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29320   

TargetAndrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM29320(BMS-665139 | oxazolidin-2-imine, 6c)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAndrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM29320(BMS-665139 | oxazolidin-2-imine, 6c)
Affinity DataKi:  0.300nM ΔG°:  -12.9kcal/mole EC50:  0.200nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM29320(BMS-665139 | oxazolidin-2-imine, 6c)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails
PubMed