BDBM27576 5-[(5-fluoro-3-methyl-1H-indazol-4-yl)oxy]benzene-1,3-dicarbonitrile::Indazole Derivative, 6
SMILES Cc1n[nH]c2ccc(F)c(Oc3cc(cc(c3)C#N)C#N)c12
InChI Key InChIKey=JYAHFMKZJRVTDT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 27576
Affinity DataIC50: 50nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer
Pfizer
Affinity DataIC50: 384nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Pfizer
Pfizer
Affinity DataIC50: 145nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Instituto De Tecnologia Em F£Rmacos
Curated by ChEMBL
Instituto De Tecnologia Em F£Rmacos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair