BDBM26266 Ambien::CHEMBL911::Dalparan::N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide::ZPM::Zolpidem::Zolpidem tartrate
SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1
InChI Key InChIKey=ZAFYATHCZYHLPB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 148 hits for monomerid = 26266
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]-Flumazenil binding to recombinant GABA-A receptor alpha-1 subunit in cerebellumMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 3More data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:Effective concentration against Gamma-aminobutyric acid A receptor, alpha 5More data for this Ligand-Target Pair
Affinity DataEC50: 198nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
Affinity DataEC50: 737nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
Affinity DataEC50: 191nMAssay Description:Activity at rat wild type GABAA alpha-1-beta-2-gamma-2 receptor expressed in xenopus oocytes assessed as GABA-elicited response by two electrode volt...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 1.80E+9nMAssay Description:Potentiation of GABA-evoked Cl- currents in Xenopus oocytes expressing human alpha-2-beta-2-gamma-2 subunitsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of Ro 5-4864 from peripheral (renal cell) Benzodiazepine receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataEC50: 240nMAssay Description:Positive allosteric modulation of human recombinant GABA-A receptor alpha1beta2gamma2 expressed in HEK293 cells assessed as potentiation of of GABA i...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]flumazenil binding to recombinant GABA-A receptor alpha-1 subunit in spinal cordMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of [3H]flumazenil binding to recombinant GABA-A receptor alpha-1-beta-2-gamma-2 subunitsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataKd: 6.30E+4nMAssay Description:Binding affinity to albumin (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-3(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,M169C](Human)
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 15.5nM ΔG°: -10.6kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rat)
Heidelberg
Curated by ChEMBL
Heidelberg
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Binding affinity for rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of GABAA receptor alpha1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of GABAA receptor alpha1 (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 26.7nMAssay Description:Binding affinity measured using LtK- cell membranes expressing GABA alpha-1-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rat)
Heidelberg
Curated by ChEMBL
Heidelberg
Curated by ChEMBL
Affinity DataKi: 26.7nMAssay Description:Displacement of [3H]Ro-151788 from rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rat)
Heidelberg
Curated by ChEMBL
Heidelberg
Curated by ChEMBL
Affinity DataKi: 26.7nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 26.7nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha-1-beta-3-gamma-2 receptor expressed in HEK cells by liquid scintillation countin...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Binding affinity for human GABA-A receptor alpha-4-beta-3-gamma-2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Inhibition of [3H]Ro-151788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 subtype expressed in L (tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Displacement of [3H]Ro 15-1788 from human recombinant GABAA alpha-1-beta-3-gamma-2 receptor expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
Affinity DataKi: 27nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha1 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universidad De Sevilla
Curated by PDSP Ki Database
Universidad De Sevilla
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
Georgetown University
Curated by PDSP Ki Database
Georgetown University
Curated by PDSP Ki Database
Affinity DataKi: 35nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R171C](Human)
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 35.8nM ΔG°: -10.2kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R183C](Human)
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 38nM ΔG°: -10.1kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
Georgetown University
Curated by PDSP Ki Database
Georgetown University
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1 [S205C]/beta-2 [26-512]/gamma-2 [40-467](Human)
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 41.2nM ΔG°: -10.1kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rat)
Heidelberg
Curated by ChEMBL
Heidelberg
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of [3H]flumazenil specific binding at rat GABA-A alpha-1-beta-2-gamma-2 receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair