BDBM25299 1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoethyl)-3-phenylpyridin-1-ium::CHEMBL192342::bisphosphonate, 46

SMILES OC(C[n+]1cccc(c1)-c1ccccc1)(P(O)(O)=O)P(O)([O-])=O

InChI Key InChIKey=ZYEONEYSNIUGRA-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25299   

TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandPNGBDBM25299(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)
Affinity DataIC50: 1.41E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphotransferase(Trypanosoma cruzi)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM25299(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibitory activity against Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM25299(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards Farnesyl diphosphate synthase from leishmania majorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed