BDBM24060 (2S)-2-amino-2-cyclopropyl-1-[(2S)-4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl]ethan-1-one::CHEMBL204459::dihydropyrrole, 19

SMILES N[C@@H](C1CC1)C(=O)N1CC(=C[C@H]1c1ccccc1)c1cc(F)ccc1F

InChI Key InChIKey=VCOUEHUEFUDZIS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24060   

LigandPNGBDBM24060((2S)-2-amino-2-cyclopropyl-1-[(2S)-4-(2,5-difluoro...)
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:The kinesin motor domain is incubated with microtubules, 1 mM ATP (1: 1 MgCl2 : Na-ATP), and compound at 23°C in buffer. After reaction was term...More data for this Ligand-Target Pair
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

LigandPNGBDBM24060((2S)-2-amino-2-cyclopropyl-1-[(2S)-4-(2,5-difluoro...)
Affinity DataIC50: 3.50E+3nMpH: 7.4 T: 2°CAssay Description:The hERG IC50 values were determined by radioligand competition experiments using membrane preparations from human embryonic kidney cells that stably...More data for this Ligand-Target Pair
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TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24060((2S)-2-amino-2-cyclopropyl-1-[(2S)-4-(2,5-difluoro...)
Affinity DataIC50: 2nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed