BDBM23926 (E)-resveratrol::5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol::CHEMBL165::Resveratol::Stilbene, 2f::US11866416, Example 7::cid_445154::resveratrol::trans-resveratrol
SMILES Oc1ccc(\C=C\c2cc(O)cc(O)c2)cc1
InChI Key InChIKey=LUKBXSAWLPMMSZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 181 hits for monomerid = 23926
Affinity DataIC50: 960nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
Affinity DataIC50: 960nMpH: 8.0 T: 2°CAssay Description:The activity of recombinant human QR2 under steady-state conditions was evaluated on a MolecularDevices SpectraMax Plus 384 UV-visible spectrophotome...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
Affinity DataEC50: 1.63E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
TargetM18 aspartyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 2.24E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
TargetProcathepsin L(Human)
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.96E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
TargetLarge T antigen(SV40)
Southern Research Specialized Biocontainment Screening Center
Curated by PubChem BioAssay
Southern Research Specialized Biocontainment Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 2.62E+4nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
Affinity DataEC50: 1.23E+4nMAssay Description:Keywords: STK33 Kinase, Non-ATP Competitive Inhibitor Assay Overview: Purified STK33 Kinase is preincubated with potential inhibitors and allowed to ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:The actual target(s) whereby the most active substituted trans-stilbenes inhibit the TNFα-induced activation of NF-κB remains to be identif...More data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Sheep)
University of Pennsylvania School of Medicine
Curated by ChEMBL
University of Pennsylvania School of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.73E+4nMAssay Description:Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Sheep)
University of Pennsylvania School of Medicine
Curated by ChEMBL
University of Pennsylvania School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human aromatase using dibenzylfluorescein substrate preincubated for 30 mins measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+5nMAssay Description:Tested in vitro for the inhibition of protein-tyrosine kinase p56lck using angiotensin I (1.2 mM) and [gamma-32P]-ATP (50 pM)More data for this Ligand-Target Pair
Affinity DataIC50: 3.66E+5nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLuciferin 4-monooxygenase(Common eastern firefly)
University of Eastern Finland
Curated by ChEMBL
University of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of phorbol ester-induced ornithine decarboxylase in human MCF7 cells after 6 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+5nMAssay Description:Inhibition of thrombin-induced platelet aggregation in humanMore data for this Ligand-Target Pair
Affinity DataIC50: 2.84E+3nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant NQO2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataEC50: 5.78E+6nMAssay Description:Binding affinity to recombinant C1 domain of PKCalpha expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence quenching assayMore data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) assessed as N-methyldihydronicotinamide oxidation per mg of protein a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Noradrenaline induced vasorelaxant activity in intact rat aortic ringsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Sheep)
National Research Institute of Chinese Medicine
Curated by ChEMBL
National Research Institute of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine
Curated by ChEMBL
National Research Institute of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 5.56E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine
Curated by ChEMBL
National Research Institute of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 996nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Sheep)
University of Pennsylvania School of Medicine
Curated by ChEMBL
University of Pennsylvania School of Medicine
Curated by ChEMBL
Affinity DataIC50: 535nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine
Curated by ChEMBL
National Research Institute of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataIC50: 1.99E+4nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced increase of intracellular calcium l...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataIC50: 1.99E+4nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced increase of intracellular calcium l...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataIC50: 2.74E+3nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level in presence of AITCMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level in absence of AITCMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine
Curated by ChEMBL
National Research Institute of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 996nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate assessed as PGE2 production preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Sheep)
University of Pennsylvania School of Medicine
Curated by ChEMBL
University of Pennsylvania School of Medicine
Curated by ChEMBL
Affinity DataIC50: 535nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate assessed as PGE2 production preincubated for 10 mins followed by substrate addition inc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant NQO2 using DCPIPas substrate and NRH as cofactor measured for 1 min by spectrophotometry in the prsence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 913nMAssay Description:Inhibition of human recombinant NQO2 using DCPIPas substrate and NRH as cofactor measured for 1 min by spectrophotometry in the absence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of self-induced amyloid beta 42 (unknown origin) aggregation measured for 24 hrs by thioflavin T-based fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of self-induced amyloid beta 40 (unknown origin) aggregation measured for 24 hrs by thioflavin T-based fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in Escherichia coli DH5aplha cells assessed as O-deethylation of ethoxyresorufin in presence of NADP...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli DH5aplha cells assessed as O-deethylation of ethoxyresorufin in presence of NADP...More data for this Ligand-Target Pair
Affinity DataIC50: 2.12E+5nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+5nMAssay Description:Displacement of FITC-conjugated BH3-Bak peptide from human recombinant Bcl-XL expressed in Escherichia coli BL21 (DE3) by fluorescence polarization a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+4nMAssay Description:Displacement of FITC-conjugated BH3-Bak peptide from 1 uM Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) by fluorescence pol...More data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+4nMAssay Description:Displacement of FITC-conjugated BH3-Bak peptide from Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) by fluorescence polariza...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 23926
ITC DataΔG°: -9.78kcal/mole −TΔS°: 5.00kcal/mole ΔH°: -14.6kcal/mole logk: 2.56E+7
pH: 7.5 T: 25.00°C
pH: 7.5 T: 25.00°C