BDBM23232 1,2,5-oxadiazole, OXD1::4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid

SMILES OC(=O)c1no[nH]c1=O

InChI Key InChIKey=IBRWUZLLHSXPKL-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23232   

TargetL-lactate dehydrogenase B chain(Human)
University of Bristol

LigandPNGBDBM23232(4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid | 1,2...)
Affinity DataIC50: 7.21E+4nMAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23232(4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid | 1,2...)
Affinity DataKi:  210nM ΔG°:  -9.10kcal/mole IC50: 650nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed