BDBM231629 IDI-6273

SMILES CCOc1cccc(=O)c2c(C)n(Cc3ccc(Cl)cc3)c(C)c12

InChI Key InChIKey=PTQJXFLYSQXYEP-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231629   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Harvard School of Public Health

LigandPNGBDBM231629(IDI-6273)
Affinity DataIC50: 1.35E+4nMAssay Description:Substrate-dependent inhibition of recombinant PfDHODH protein was assessed in an in vitro assay in 384-well clear plates (Corning 3702) as described ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Harvard School of Public Health

LigandPNGBDBM231629(IDI-6273)
Affinity DataIC50: 3.00E+4nMAssay Description:Substrate-dependent inhibition of recombinant PfDHODH protein was assessed in an in vitro assay in 384-well clear plates (Corning 3702) as described ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed