BDBM228129 US9562012, mitoglitazone
SMILES CCc1ccc(nc1)C(=O)COc1ccc(CC2SC(=O)NC2=O)cc1
InChI Key InChIKey=IRNJSRAGRIZIHD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 228129
Affinity DataIC50: 2.66E+4nMAssay Description:PPARγ binding is measured by a TR-FRET competitive binding assay using Invitrogen LanthaScreen TR-FRET PPARγ Competitive Binding Assay (I...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataIC50: 2.23E+4nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataEC50: 657nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of photoprobe from MPC2 (unknown origin)More data for this Ligand-Target Pair